Skin & Collagen
GHK-Cu
GHK-Cu (Glycyl-L-histidyl-L-lysine copper) is a naturally occurring copper peptide found in human plasma, saliva, and urine. It has been extensively studied for its role in wound healing, collagen synthesis, skin regeneration, and anti-inflammatory activity. Research demonstrates its ability to activate over 4,000 genes involved in tissue remodeling.
Skin & Collagen
GHK-Cu
GHK-Cu (Glycyl-L-histidyl-L-lysine copper) is a naturally occurring copper peptide found in human plasma, saliva, and urine. It has been extensively studied for its role in wound healing, collagen synthesis, skin regeneration, and anti-inflammatory activity. Research demonstrates its ability to activate over 4,000 genes involved in tissue remodeling.
Key research findings
Naturally occurring copper peptide declining with age (60% reduction by age 60)
Research shows activation of over 4,000 human genes involved in tissue remodeling
Stimulates collagen and elastin synthesis, key proteins for skin structure
Promotes wound healing, anti-inflammatory response, and angiogenesis
Preclinical studies demonstrate antioxidant and DNA repair properties
Published research & clinical studies
STUDY 1
GHK-Cu May Prevent Oxidative Stress Through Regulation of Gene Expression
Journal of Biological Chemistry, 2014
Research on GHK-Cu's ability to modulate gene expression for oxidative stress protection.
STUDY 2
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways
BioMed Research International, 2015
Comprehensive review of GHK peptide's multiple cellular pathway modulation activities.
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STUDY 3
Wound Healing Properties of GHK-Cu
Journal of Clinical & Aesthetic Dermatology, 2012
Research on selank's effects on neuroReview of GHK-Cu's wound healing and skin regeneration properties in clinical contexts.transmitter systems involved in mood regulation.
STUDY 4
Therapeutic Peptides Including GHK-Cu in Orthopaedics
JAAOS / PMC, 2025
Recent review of GHK-Cu among wound-healing peptides promoting ECM remodeling.
STUDY 5
Copper Peptide GHK-Cu and Tissue Remodeling
Molecules, 2023
Research on GHK-Cu's molecular mechanisms in tissue repair and collagen production.
Research disclaimer: The studies referenced above are provided for educational purposes only. They represent published scientific research and do not constitute medical advice, treatment recommendations, or endorsement of any specific therapy. Velacore Health does not provide medical services or prescribe medications. All decisions regarding peptide therapy are made solely by independent, licensed healthcare providers. Always consult with your healthcare provider before considering any therapy.