Metabolic Optimization
MOTS-C
MOTS-C is a mitochondrial-derived peptide that plays a role in metabolic regulation and exercise performance. Research has explored its effects on cellular energy production, insulin sensitivity, and metabolic homeostasis, with studies demonstrating connections to exercise physiology and aging.
Key research findings
Mitochondrial-derived signaling peptide involved in metabolic homeostasis
Research shows connections to improved insulin sensitivity and glucose regulation
Studies demonstrate exercise-mimetic properties at the cellular level
Associated with improved mitochondrial function and cellular energy production
Declining levels observed with aging, suggesting a role in age-related metabolic decline
Published research & clinical studies
STUDY 1
MOTS-c: A Mitochondrial-Derived Peptide Regulator of Energy Homeostasis
Cell Metabolism, 2015
Foundational study identifying MOTS-c as a mitochondrial-derived peptide that regulates metabolic homeostasis.
STUDY 2
The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis
Cell Reports, 2018
Research demonstrating MOTS-c's role in promoting metabolic balance through AMPK activation.
STUDY 3
MOTS-c is an Exercise-Induced Mitochondrial-Encoded Regulator of Age-Dependent Physical Decline
Nature Communications, 2021
Study showing MOTS-c acts as an exercise-induced factor that may counteract age-related physical decline.
STUDY 4
Endogenous MOTS-c Signaling and Its Role in Metabolic Health
Aging Cell, 2021
Research on the endogenous signaling role of MOTS-c in metabolic health and aging.
STUDY 5
Mitochondrial-Derived Peptides in Aging and Age-Related Diseases
Biogerontology, 2023
Review of mitochondrial-derived peptides including MOTS-c in the context of aging and metabolic disease.
Research disclaimer: The studies referenced above are provided for educational purposes only. They represent published scientific research and do not constitute medical advice, treatment recommendations, or endorsement of any specific therapy. Velacore Health does not provide medical services or prescribe medications. All decisions regarding peptide therapy are made solely by independent, licensed healthcare providers. Always consult with your healthcare provider before considering any therapy.