Stress & Mood
Selank
Selank is a synthetic heptapeptide analog of the naturally occurring immunomodulatory peptide tuftsin. It has been studied for its anxiolytic (anti-anxiety), nootropic, and immune-modulating properties. Research focuses on its effects on GABA neurotransmission and the expression of BDNF, with applications in stress resilience and mood regulation.
Stress & Mood
Selank
Selank is a synthetic heptapeptide analog of the naturally occurring immunomodulatory peptide tuftsin. It has been studied for its anxiolytic (anti-anxiety), nootropic, and immune-modulating properties. Research focuses on its effects on GABA neurotransmission and the expression of BDNF, with applications in stress resilience and mood regulation.
Key research findings
Synthetic analog of the immunomodulatory peptide tuftsin
Research demonstrates anxiolytic effects comparable to benzodiazepines without sedation
Modulates GABA neurotransmitter system and enhances serotonin metabolism
Increases BDNF expression, supporting neuroplasticity and cognitive function
Approved in Russia as a treatment for anxiety and neurasthenic conditions
Published research & clinical studies
STUDY 1
Selank and Its Metabolites in the Regulation of BDNF Expression
Bulletin of Experimental Biology and Medicine, 2016
Research on selank's role in modulating BDNF expression for neuroprotection.
STUDY 2
Anxiolytic Effect of Selank: Comparative Study with Benzodiazepines
Zhurnal Nevrologii, 2008
Comparative study showing selank's anxiolytic effects relative to standard anxiolytics.
STUDY 3
Selank Modulation of Serotonin and GABA Neurotransmission
Psychopharmacology, 2014
Research on selank's effects on neurotransmitter systems involved in mood regulation.
STUDY 4
Immunomodulatory Properties of Selank
Immunopharmacology and Immunotoxicology, 2012
Study of selank's immunomodulatory effects alongside its neurological applications.
STUDY 5
Neuroactive Peptides Including Selank for Neuroplasticity
PMC / JAAOS, 2025
Recent review covering selank among neuroactive peptides enhancing BDNF and HGF pathways.
Research disclaimer: The studies referenced above are provided for educational purposes only. They represent published scientific research and do not constitute medical advice, treatment recommendations, or endorsement of any specific therapy. Velacore Health does not provide medical services or prescribe medications. All decisions regarding peptide therapy are made solely by independent, licensed healthcare providers. Always consult with your healthcare provider before considering any therapy.